Author's response to reviews Title: Pleural Fluid Cell-free DNA Integrity Index to Identify Cytologically Negative Malignant Pleural Effusions Including Mesotheliomas Authors:

Author's response to reviews Title: Diagnostic Accuracy of Pleural Fluid NT-pro-BNP for Pleural Effusions of Cardiac Origin: A Systematic Review and Meta-analysis Authors:

Value of DNA analysis in addition to cytological testing in the diagnosis of malignant pleural effusions.

BACKGROUND Aneuploidy appears to be a highly specific marker for cancer, and measurement of cellular DNA content by flow cytometry is rapid and reliable. This study was undertaken to determine if the addition of DNA analysis improved the sensitivity of cytological diagnosis of malignancy in pleural fluid. METHODS Pleural effusions from 92 patients were studied by cytological examination and f...

Th1 and Th2 Cytokine Profiles in Malignant Pleural Effusion

Background: The alteration of Th1 and Th2 cytokine levels is the subject of controversy in pleural effusions caused by malignancy, a situation that favors a Th2 immune response. Objective: To examine the different levels of IL-4 and IL-10 (Th2 cytokines), and IL-2 and interferon-γ (IFN-γ) (Th1 cytokines) in malignant and non-malignant pleural effusions. Method: The cytokine levels in pleural fl...

Cytologically proved malignant pleural effusions.

We read with interest the report by Assi and colleagues1 on the distribution of transudates and exudates between cytolog¬ ically proved malignant pleural effusions. The authors found that one of the 98 patients with malignant pleural effusions enrolled in the study, had a borderline transudate and had congestive heart failure at the time of the thoracentesis. The authors concluded that cytologi...

مقایسه ارزش تشخیصی تومور مارکرهای مایع پلور با سیتولوژی مایع پلور و بیوپسی ‌پلور در اثبات وجود بدخیمی

    Introduction: Cancers are the most prevalent causes of exudative pleural effusions after para-pneumonic pleural effusions. Despite the combination of the pleural fluid cytological studies and pleural biopsy, diagnosis could not be reached in an important number of cases. In an attempt to improve the value of pleural fluid analysis in the diagnosis of malignant pleural effusion, some studies...